Type 2 Diabetes (T2D) Clinical Trials

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The Effect of Exercise of High vs. Moderate Intensity on the Brain in Type 2 Diabetes

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if exercise training of high or moderate intensity is most optimal to improve brain health and prevent neurodegeneration in type 2 diabetes patients. The main question it aims to answer is: What is the effect of exercise training of high vs. moderate intensity on brain metabolism, brain perfusion, and cognition in type 2 diabetes? Researchers will compare the exercise training groups to a control group without exercise training to determine the effect of exercise training on the brain in type 2 diabetes. Participants will exercise for 6 months, 3 times per week. Before and after these 6 months, they will undergo: * a brain MRI scan * cognitive tests * blood sampling

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 75
Healthy Volunteers: f
View:

• type 2 diabetes

• no insulin therapy

• 30-75 years old

• physically inactive

Locations
Other Locations
Belgium
Hasselt University
RECRUITING
Hasselt
Contact Information
Primary
Dominique Hansen, Full Professor
dominique.hansen@uhasselt.be
+3211292126
Backup
Jitske Vandersmissen, PhD student
jitske.vandersmissen@uhasselt.be
+3211268387
Time Frame
Start Date: 2024-11-08
Estimated Completion Date: 2027-08
Participants
Target number of participants: 75
Treatments
Experimental: High intensity exercise training group
This arm will receive 6 months of exercise training at high intensity (105% VT2)
Experimental: Moderate intensity exercise training group
This arm will receive 6 months of exercise training at moderate intensity (60% VT2)
No_intervention: Control group
This arm won't receive exercise training
Related Therapeutic Areas
Sponsors
Collaborators: Jessa Hospital, Universitaire Ziekenhuizen KU Leuven, Research Foundation Flanders
Leads: Hasselt University

This content was sourced from clinicaltrials.gov