Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to evaluate whether a multifaceted community-based intervention, comprising 1) screening and lifestyle counseling by female community health volunteers (FCHVs); community health workers in Nepal, through home visits, and 2) regular Short Message Service (SMS) messages, can effectively reduce systolic blood pressure (SBP), lower fasting blood glucose, and increase smoking cessation rates among adults living in Pokhara with hypertension, type 2 diabetes, and smoking habits, respectively. The main research questions are: * Can FCHV home visits combined with regular mobile phone messages focused on blood pressure management reduce systolic blood pressure in adults with hypertension? * Can FCHV home visits combined with regular mobile phone messages focused on diabetes management lower fasting blood glucose levels in adults with type 2 diabetes? * Can FCHV home visits combined with regular mobile phone messages focused on smoking cessation increase the cessation rate among current smokers? Researchers will compare the intervention group with a usual care group, which does not receive regular FCHV home visits for managing the three aforementioned risk factors or mobile phone messages.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 75
Healthy Volunteers: f
View:

• Meeting at least one of the following three conditions

‣ Hypertensive, defined as

⁃ BP≥140/90 mmHg at two separate measurements

⁃ Type 2 diabetes, defined as

⁃ Fingerprick glucose≥100 mg/dL, and plasma fasting glucose ≥126 mg/dL, and HbA1c≥6.5

⁃ Current smoker, defined as

⁃ Ever smoked ≥100 cigarettes in lifetime, and

⁃ Currently smokes every day.

• Registered on the voter list in Pokhara.

• Not planning to migrate outside of Pokhara during the study period

Locations
Other Locations
Nepal
Pokhara Metropolitan City
RECRUITING
Pokhara
Contact Information
Primary
Dinesh Neupane, PhD
dneupan2@jhu.edu
410-502-9170
Time Frame
Start Date: 2025-04-28
Estimated Completion Date: 2026-03-31
Participants
Target number of participants: 2070
Treatments
Experimental: SCALE-NCD (Intervention)
Intervention arm will receive the following two components of the SCALE-NCD intervention package:~1. FCHV home visits every three months, including measurements, counseling and referral;~2. Mobile phone messages, including lifestyle modification
No_intervention: Control
Control arm will receive the usual care in Pokhara Metropolitan City in Nepal.
Related Therapeutic Areas
Sponsors
Leads: Johns Hopkins Bloomberg School of Public Health
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)

This content was sourced from clinicaltrials.gov