The Application of an AI-driven Multimodal Predictive Model for Cognitive Impairment in Patients With Type 2 Diabetes Mellitus
Status: Recruiting
Location: See all (21) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
The objective of this observational study is to evaluate the accuracy and feasibility of an artificial intelligence-based multimodal cognitive screening system in early identification of diabetes-related mild cognitive impairment (MCI) among type 2 diabetes mellitus (T2DM) patients through a 3-5 year follow-up. It also aims to analyze the correlation between diabetic metabolic indicators (such as glycemic variability and HbA1c levels) and cognitive function changes, thereby determining the value of this intelligent screening system in early detection and intervention of cognitive impairment in T2DM patients, which constitutes the key focus of this research.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 75
Healthy Volunteers: t
View:
• Diagnosed with type 2 diabetes mellitus (T2DM).
• Aged 40-75 years, with self-reported or informant-reported memory complaints.
• Cognitive assessment scores consistent with either:
‣ Cognitive Normal (CN) or
⁃ Mild Cognitive Impairment (MCI).
• Preserved ability to perform basic activities of daily living (ADLs).
• Memory-specific deficits only (e.g., partial forgetfulness), with intact other cognitive domains (e.g., reasoning, judgment, attention, and executive function).
Locations
Other Locations
China
Minda Hospital Affiliated to Hubei Minzu University
RECRUITING
Enshi
Huanggang Central Hospital
RECRUITING
Huanggang
Huangshi Central Hospital
RECRUITING
Huangshi
Jingzhou Central Hospital
RECRUITING
Jingzhou
Sinopharm Dongfeng General Hospital
NOT_YET_RECRUITING
Shiyan
Suizhou Central Hospital
NOT_YET_RECRUITING
Suizhou
China Resources & WISCO General Hospital
RECRUITING
Wuhan
Hubei Provincial Hospital of Integrated Chinese & Western Medicine
RECRUITING
Wuhan
Tianyou Hospital Affiliated to Wuhan University of Science and Technology
NOT_YET_RECRUITING
Wuhan
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Wuhan Central Hospital
RECRUITING
Wuhan
Wuhan Fifth Hospital
RECRUITING
Wuhan
Wuhan Fourth Hospital
RECRUITING
Wuhan
Xiangyang Central Hospital
NOT_YET_RECRUITING
Xiangyang
Xiangyang First People's Hospital
RECRUITING
Xiangyang
Xianning Central Hospital
RECRUITING
Xianning
Xiantao First People's Hospital
NOT_YET_RECRUITING
Xiantao
Xiaogan Central Hospital
RECRUITING
Xiaogan
Renhe Hospital Affiliated to China Three Gorges University
RECRUITING
Yichang
Sinopharm Gezhouba Central Hospital
NOT_YET_RECRUITING
Yichang
Yichang Central People's Hospital
RECRUITING
Yichang
Contact Information
Primary
Prof. Yang, Doctor
yangyantj@qq.com
86-18827397697
Time Frame
Start Date:2025-04-22
Estimated Completion Date:2028-12-30
Participants
Target number of participants:5000
Treatments
Cognitive Normal Group
Healthy control group without significant cognitive impairment in the study
Mild Cognitive Impairment Group
An intermediate state with subjective or objective cognitive decline (e.g., memory, executive function) that does not meet the diagnostic criteria for dementia