Study of Changes in Abdominal Fluid in Connection With Peritonitis. A Descriptive Study in Patients With Purulent or Fecal Peritonitis.
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Perforated diverticulitis of the colon can be complicated by peritonitis, either purulent or fecal. Both are life threatening conditions requiring emergency surgery. The background in terms of reasons for inflammation (diverticulitis) and perforation to develop is unknown. In this study we focus on specific changes associated with inflammation, both in tissues and of fecal and mucosal microbiota.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Signs of perforated diverticulitis with peritonitis and decision to perform emergency surgery (Group I)
• Signs of acute diverticulitis and no decision of emergency surgery (Group II)
• Patients with colorectal cancer planned for elective surgery (Group III)
Locations
Other Locations
Sweden
Sahlgrenska University Hospital/Östra
RECRUITING
Gothenburg
Contact Information
Primary
Eva Haglind, MD, PhD
eva.haglind@vgregion.se
+46705349088
Backup
Anette Wedin
anette.wedin@vgregion.se
+46700651143
Time Frame
Start Date: 2021-09-21
Estimated Completion Date: 2027-12
Participants
Target number of participants: 50
Treatments
Group I
Patients undergoing emergency surgery due to perforated diverticulitis with peritonitis.~No intervention, samples from abdominal fluid, blood, tissue, feces
Group II
Patients with colorectal cancer undergoing elective surgery. No intervention. Samples as for Group I
Group III
Patients with mild diverticulitis, not undergoing surgery. No intervention. Samples from blood and feces.
Related Therapeutic Areas
Sponsors
Collaborators: Göteborg University
Leads: Sahlgrenska University Hospital