The Role of Thomboxane A2 and it's Receptor in Vascular Regulation in Women With Endometriosis
Status: Recruiting
Location: See location...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• Born with a uterus
• 18-45 years old
• With and without endometriosis
Locations
United States
Pennsylvania
Noll Laboratory
RECRUITING
University Park
Contact Information
Primary
Lacy Alexander, Ph.D.
lma191@psu.edu
8148671781
Backup
Sue Slimak, RN
sks31@psu.edu
8148638556
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2027-08-01
Participants
Target number of participants: 96
Treatments
Experimental: Aspirin
one dose of aspirin
Placebo_comparator: Placebo
Placebo pill
Related Therapeutic Areas
Sponsors
Leads: Penn State University