Bone Marrow and Follicular Lymphoma

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a prospective single-center study designed to assess potential differences in cell composition between bone marrows of patients with follicular lymphoma and those from control subjects. Follicular lymphoma is the most common indolent lymphoma. It is characterised by systematic relapses and bone marrow dissemination in 70% of patients at the time of diagnosis. Although relapses are thought to be related to refractory tumour cells nested in a supportive microenvironment in the bone marrow, the mechanisms involved are poorly understood. To study the specificities of the bone marrow of patients with follicular lymphoma, It is necessary to compare them with control samples. This study takes advantage of surgeries involving sternotomies to recover lost bone marrow and establish a bone marrow bank of patients without hematological disease. This bank will be used to set up control cohorts for other clinical trials involving patients with follicular lymphoma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Major patient

• Patient hospitalized in the thoracic, cardiac and vascular surgery department for surgery involving a sternotomy

• Patient with free, informed, written consent

• Patient covered by a health insurance scheme

Locations
Other Locations
France
CHU Rennes
RECRUITING
Rennes
Contact Information
Primary
Juliette Ferrant, MD
juliette.ferrant@chu-rennes.fr
0299282555
Backup
Alexandra Guerrier
alexandra.guerrier@chu-rennes.fr
0299282555
Time Frame
Start Date: 2024-12-04
Estimated Completion Date: 2034-10-01
Participants
Target number of participants: 200
Treatments
Experimental: Experimental
Sponsors
Leads: Rennes University Hospital

This content was sourced from clinicaltrials.gov