Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The overall purpose of this pilot study is to examine the feasibility, acceptability, and tolerability of light and moderate intensity exercise in adults with MGeffect of light vs. moderate intensity exercise on health outcomes. Participants will be enrolled into the NeuroWell exercise program, which is geared toward individuals with neurological disorders or injuries and led by Certified Exercise Physiologists (CEPs) at the HealthPartners Neuroscience Center. A total of 20 people with MG will be enrolled in this study and participate in a small group exercise program 3 times a week for 12 weeks. Participants will be randomized into two exercise groups: 1) Light intensity or 2) Moderate intensity. We hypothesize that light and moderate intensity exercise will be feasible, acceptable, and tolerable in adults with MG and that individuals in the light intensity exercise group will be able to achieve the same improvement in health outcomes as the moderate intensity group.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
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• Ability to provide and provision of signed and dated informed consent form.

• Age 18-80

• Diagnosis of generalized MG.

• On a stable MG prescription medication regimen for the last 3 months.

Locations
United States
Minnesota
HealthPartners Neuroscience Center
RECRUITING
Saint Paul
Contact Information
Primary
Clinical Trials Coordinator
ClinicalTrials@HealthPartners.com
651-495-6363
Time Frame
Start Date: 2024-09-16
Estimated Completion Date: 2025-12
Participants
Target number of participants: 20
Treatments
Experimental: Light intensity Exercise
Aerobic intensity levels: Heart rate reserve (HRR) 30-39%, 9-11 Borg Rate of Perceived Exertion (RPE) Strength intensity levels: %One Repetition Max (1RM) 40-50%, OMNI RPE 1-4
Experimental: Moderate intensity Exercise
Aerobic intensity levels: HRR 40-59%, 12-13 Borg RPE Strength intensity levels: %1RM 60-80%, OMNI RPE 5-6
Related Therapeutic Areas
Sponsors
Leads: HealthPartners Institute

This content was sourced from clinicaltrials.gov