Efgartigimod in IVIG Dependent Myasthenia Gravis Patients

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study is an open label, single center, prospective, 26 weeks study with descriptive analysis where IVIG is replaced by efgartigimod therapy. MG-ADL and MGQOL evaluations will occur weekly throughout the study to week 26.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• 1\. Signed informed consent. 2. Age 18-80 years 3. Acetylcholine receptor antibody positive, myasthenia gravis patients, with stable disease for the past four or more months. Stable disease is defined as no change in dosage or interval in IVIG treatments and without any significant change in clinical status.

• 4\. No modification or addition of NSISTs in the past six months 5. No modification or addition in corticosteroid therapy for the past three months 6. Myasthenia Gravis diagnosis was supported by abnormal neurotransmission test or history of improvement with AChE inhibitors.

• 7\. Receiving chronic regular IVIG treatments for myasthenia gravis for the past year or more.

Locations
Other Locations
Canada
Clinique Neuro-Outaouais
RECRUITING
Gatineau
Contact Information
Primary
François Jacques, Doctor
francois.jacques@neuro-outaouais.ca
819-777-2500
Backup
Victorine Sikati Foko, Nurse
8197772500
Time Frame
Start Date: 2025-02-06
Estimated Completion Date: 2027-01-06
Participants
Target number of participants: 30
Treatments
Experimental: treatment
Efgartigimod infusion
Related Therapeutic Areas
Sponsors
Leads: Clinique Neuro-Outaouais
Collaborators: argenx

This content was sourced from clinicaltrials.gov