Effectiveness of Essilor® Stellest® Lenses in Slowing Down Myopia Progression in Young Adults

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

It is expected that myopia progression stabilises in the late teenage years, however, some studies report that myopia progression continues through early adulthood in as many as one third of myopes. Similarly, there are reports of myopia commencing in early adulthood. Although the rate of progression is slower than that occurring in childhood, between 20-35% of adults aged between 20-30 years were reported to progress by at least -1.00D over a five year period. Given that every dioptre increase in myopia results in an increased overall lifetime risk of serious ocular pathology, it seems opportune to investigate whether myopia management treatments designed to slow myopia progression in childhood could be beneficial for progressing adult myopes. The proposed study will conduct a prospective, randomised, paired-eye, trial with cross-over to evaluate the efficacy of Essilor Stellest myopia management spectacle lenses on the progression of myopia in adults aged between 18-40 years. The outcomes from the trial will provide novel evidence regarding the utility of these lenses in an adult population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: t
View:

• Cycloplegic SER less than -0.75D

• Astigmatism of 1.50D or less

• Anisometropia of 1.50D or less

• Evidence of annual progression of myopia of at least 0.50D in the previous two-year period

Locations
Other Locations
United Kingdom
Ulster University
RECRUITING
Coleraine
Contact Information
Primary
Sara J McCullough, PhD
sj.mccullough@ulster.ac.uk
+442870123078
Backup
Jane M Fulton, PhD
j.fulton@ulster.ac.uk
Time Frame
Start Date: 2024-10-17
Estimated Completion Date: 2027-04
Participants
Target number of participants: 42
Treatments
Experimental: A1: Stellest lens wear in front of dominant eye
Stellest lens wear in front of dominant eye.
Placebo_comparator: A2: Single vision lens wear in front of non-dominant eye
Single vision lens wear in front of non-dominant eye.
Experimental: B1: Stellest lens wear in front of non-dominant eye
Single vision lens wear in front of non-dominant eye
Placebo_comparator: B2: Single-vision lens wear in front of dominant eye.
Single vision lens wear in front of dominant eye.
Related Therapeutic Areas
Sponsors
Leads: University of Ulster
Collaborators: Essilor International

This content was sourced from clinicaltrials.gov