Comparative Study of Metformin Versus Doxycycline in Treatment of Moderate to Severe Adult Acne Vulgaris Patients: Multicentre, Randomized, Double-blind Trial.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in treatment of acne vulgaris patient or not. Patients will be asked to take doxycycline along with tropical treatment in one group and metformin along with tropical treatment in another group. Researcher will compare the clinical improvement in two groups.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Newly diagnosed moderate and severe AV patients diagnosed by a dermatologist
• \-
Locations
Other Locations
Bangladesh
BSMMU
RECRUITING
Dhaka
Contact Information
Primary
Muhammad Marnush, MBBS
marnushm@gmail.com
88001714558447
Time Frame
Start Date: 2023-03-05
Estimated Completion Date: 2024-03
Participants
Target number of participants: 120
Treatments
Experimental: Group A
Metformin 500 mg twice daily along with topical retinoids for 12 weeks
Active_comparator: Group B
Doxycycline 100 mg twice daily along with topical retinoids for 12 weeks
Related Therapeutic Areas
Sponsors
Leads: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh