Flexible Control of Gait in Parkinson Disease: Effect of Task Instruction on the Exploitation of Redundancy in Speed Control.

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: t
View:

• Patients and volunteers able to walk for 20mins and without other neurological disorders.

Locations
Other Locations
Belgium
Université catholique de Louvain
RECRUITING
Louvain-la-neuve
Contact Information
Primary
André Mouraux, PhD
andre.mouraux@uclouvain.be
+32 2 764 54 47
Backup
Frederic Crevecoeur
frederic.crevecoeur@uclouvain.be
Time Frame
Start Date: 2023-05-01
Estimated Completion Date: 2027-10-31
Participants
Target number of participants: 100
Treatments
PD
Patients with Parkinson's disease
Control
Healthy volunteers
Related Therapeutic Areas
Sponsors
Leads: Université Catholique de Louvain

This content was sourced from clinicaltrials.gov

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