Evaluation of the Cognitive Stimulation Treatment in Patients With Parkinson's Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY

The goal of this observational study is to evaluate the relationship between GBA mutation and cognitive stimulation treatment response in patients with Parkinson's disease. The main questions it aim to answer are: • assess whether the GBA mutation is associated with greater or lesser response to cognitive training treatment compared to a control group of PD patients without genetic mutations. • investigate the effect of cognitive stimulation program on behavioural aspects as secondary consequence induced by the possible improvement of cognitive abilities following treatment. Participants will be undergo to: - a neuropsychological evaluation describing their cognitive profile; - a genetic investigation and finally included in a cognitive stimulation programs according to regular clinical practice. Researchers will compare PD patients with GBA mutation and patients without genetic mutation to evaluate the effectiveness of cognitive stimulation treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Patients with Parkinson's disease according to the Gelb et al. criteria;

• Patients who have carried out genetic screening for MP;

• Patients who have a raw score in the range 15.50 to 22.23 at Montreal cognitive assessment (MoCA);

• Patients who have signed the informed consent and the Privacy Policy;

• Patients who are included in cognitive stimulation programs according to regular clinical practice.

Locations
Other Locations
Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING
Milan
Contact Information
Primary
Fabiana Ruggiero, MSc in Psychology
fabiana.ruggiero@policlinico.mi.it
+390255033621
Backup
Francesca Mameli, MSc in Psychology
francesca.mameli@policlinico.mi.it
+390255033621
Time Frame
Start Date: 2021-12-21
Estimated Completion Date: 2027-12
Participants
Target number of participants: 68
Treatments
PD with GBA gene mutation
Patients with Parkinson's disease and GBA gene mutation treated with cognitive training
PD without genetic mutation
Patients with Parkinson's disease without genetic mutation treated with cognitive training
Related Therapeutic Areas
Sponsors
Leads: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

This content was sourced from clinicaltrials.gov