Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis

Status: Recruiting
Location: See location...
Intervention Type: Other, Biological
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of the PI-PEG study is to explore the taste functions of the following 3 groups of participants: * healthy volunteers * patients with early Parkinson's disease * patients with incipient Lewy body disease. To this end, the results obtained from taste evoked potentials in each of the 3 groups of participants will be compared with each other and with different nutritional, motor and cognitive data. This study could reveal a difference in cortical processing of gustatory sensory information between patients who have had idiopathic Parkinson's disease progressing for 3 years or less, and patients who have had Lewy body disease progressing for 3 years or less. Indeed, a modification of taste evoked potentials (in terms of latencies) proportional to the degree of cerebral degeneration could be observed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ Healthy volunteers:

• Person who has given written consent

• Adult

• Enrolled in the national register of healthy volunteers

• Fasting \> 2 hours before PEG measurement

• Body Mass Index (BMI) \< 30 kg/m².

• No cognitive complaints and normal neurological assessment

⁃ Patients with idiopathic Parkinson's disease:

• Person who has given written consent

• Adult

• Fasting \> 2 hours before PEG measurement

• Body Mass Index (BMI) \< 30 kg/m².

• Diagnostic criteria for established or probable IPD

⁃ Patients with Lewy body disease:

• Person who has given written consent

• Adult

• Fasting \> 2 hours prior to PEG measurement

• Body Mass Index (BMI) \< 30 kg/m².

• Diagnostic criteria for probable or possible LBD

Locations
Other Locations
France
Chu Dijon Bourgogne
RECRUITING
Dijon
Contact Information
Primary
Vincent SCHNEIDER
vincent.schneider@chu-dijon.fr
03.80.29.30.89
Time Frame
Start Date: 2024-05-27
Estimated Completion Date: 2026-05
Participants
Target number of participants: 66
Treatments
Active_comparator: Healthy volunteers
Experimental: Patients with Idiopathic Parkinson's Disease (IPD) of course ≤ 3 years
Experimental: Patients with Lewy body disease (LBD) progressing ≤ 3 years
Sponsors
Leads: Centre Hospitalier Universitaire Dijon

This content was sourced from clinicaltrials.gov

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