Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis
The aim of the PI-PEG study is to explore the taste functions of the following 3 groups of participants: * healthy volunteers * patients with early Parkinson's disease * patients with incipient Lewy body disease. To this end, the results obtained from taste evoked potentials in each of the 3 groups of participants will be compared with each other and with different nutritional, motor and cognitive data. This study could reveal a difference in cortical processing of gustatory sensory information between patients who have had idiopathic Parkinson's disease progressing for 3 years or less, and patients who have had Lewy body disease progressing for 3 years or less. Indeed, a modification of taste evoked potentials (in terms of latencies) proportional to the degree of cerebral degeneration could be observed.
⁃ Healthy volunteers:
• Person who has given written consent
• Adult
• Enrolled in the national register of healthy volunteers
• Fasting \> 2 hours before PEG measurement
• Body Mass Index (BMI) \< 30 kg/m².
• No cognitive complaints and normal neurological assessment
⁃ Patients with idiopathic Parkinson's disease:
• Person who has given written consent
• Adult
• Fasting \> 2 hours before PEG measurement
• Body Mass Index (BMI) \< 30 kg/m².
• Diagnostic criteria for established or probable IPD
⁃ Patients with Lewy body disease:
• Person who has given written consent
• Adult
• Fasting \> 2 hours prior to PEG measurement
• Body Mass Index (BMI) \< 30 kg/m².
• Diagnostic criteria for probable or possible LBD