Parkinson's Families Project

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism. There is a pressing need to study the genetic makeup of family members both with and without Parkinson's. As families share a common genetic background, it is easier to find new Parkinson's genes by studying the genetic makeup of people with Parkinson's alongside other members of their families. We are particularly interested in studying the genetic makeup of two groups of people: 1. those who developed Parkinson's before the age of 45; and 2. those who have a family history of other relatives affected by Parkinson's. By identifying genetic factors that cause Parkinson's, we hope to understand more about the condition. Doing so will lead to the development of better diagnosis, improved disease models, and we hope in time, to the development of better treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: t
View:

• Clinical diagnosis of Parkinson's disease or parkinsonism, and either family history of Parkinson's/parkinsonism (first or second degree family member affected by Parkinson's or parkinsonism) AND/OR Early onset Parkinson's/parkinsonism (symptom onset before the age of 45 years) First or second degree family member of an Index Case, affected or unaffected by Parkinson's/parkinsonism.

• Aged over 16 years

Locations
Other Locations
United Kingdom
Royal Free London NHS Foundation Trust
RECRUITING
London
University College London Hospitals NHS Foundation Trust
RECRUITING
London
Contact Information
Primary
Study Coordinator
ion.pdresearch@ucl.ac.uk
02080168174
Time Frame
Start Date: 2015-04
Estimated Completion Date: 2027-01
Participants
Target number of participants: 2000
Treatments
Index case
Patients with a family history of Parkinson's/parkinsonism, and/or early onset Parkinson's/parkinsonism. The first individual member from a family who is recruited to the study.
Affected relatives
Patients with Parkinson's/parkinsonism who are first or second degree relatives of an Index Case.
Unaffected relatives
Participants who do not have Parkinson's/parkinsonism and are first or second degree relatives of an Index Case.
Related Therapeutic Areas
Sponsors
Collaborators: Royal Free Hospital NHS Foundation Trust, Parkinson's UK
Leads: University College, London

This content was sourced from clinicaltrials.gov