Optimization of Photodynamic Therapy Through the Association With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Status: Recruiting
Location: See location...
Intervention Type: Combination product
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
Evaluation of a therapeutic protocol based on the combination of photodynamic therapy and sonodynamic therapy, referred to as sonophotodynamic therapy. Since this new protocol is applied in a single day, it is called the single-visit Sono-PDT protocol. This protocol will be used for the treatment of nodular basal cell carcinoma lesions.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adults of both sexes, aged 18 years and older.
• Histologically confirmed nodular basal cell carcinoma with lesion diameter ≤1.0 cm.
• Participants with multiple lesions may be included, provided that each lesion meets all inclusion criteria.
Locations
Other Locations
Brazil
Hospital Amaral Carvalho
RECRUITING
Jaú
Contact Information
Primary
Ana G Salvio, Doctor
gasalvio@hotmail.com
+55 (14) 3602-1374
Time Frame
Start Date: 2025-11-24
Estimated Completion Date: 2026-12
Participants
Target number of participants: 142
Treatments
Active_comparator: Photodynamic therapy (PDT) protocol
In this arm, lesions will be treated with the conventional PDT protocol for this type of lesion.
Experimental: Sono-Photodynamic Therapy (SonoPDT) protocol
In this arm, lesions will be treated with a modified treatment protocol called SonoPDT protocol.
Related Therapeutic Areas
Sponsors
Leads: University of Sao Paulo