Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Nearly half of critically ill children are intubated and enterally fed according to recent guidelines. However, no evidence-based recommendation are available regarding fasting times prior to extubation. When an extubation is planned, children do not always present with normal neurological status yet, and are at risk of vomiting and aspiration. Extubation may also fail and require re-intubation with similar risks. Thus, pre-operative fasting guidelines are often transposed to the paediatric critical care setting, aiming for an empty stomach at extubation, with perceived decreased risks of aspiration. However, the gastric and gut motility pathophysiology is significantly different in critically ill children (frequent gastroparesis, liquid continuous feeding, etc.) compared to planned surgery children. The extrapolation of practice validated in the latter population may be inadequate. The stomach may be empty more or less rapidly than expected, leading to unnecessary prolonged fasting times or inappropriately short fasting times respectively. Gastric ultrasounding monitoring may help assessing gastric content prior to extubation. Investigators hypothesise gastric content clearance may be different in critically ill children prior to extubation, compared to pre-operative paediatric guidelines for elective surgery.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 17
View:

• 0 to 17 year old children admitted to pediatric intensive care unit

• intubated (oral or nasal tracheal tube)

• gastric enteral feeding affording at least 25% of the nutritional target (estimated with Schofield equations)

• No opposition from one of the 2 parents (or legal representatives)

Locations
Other Locations
France
Paediatric intensive care Unit - Hopital Femme Mère Enfant - Hospices Civils de Lyon
RECRUITING
Bron
Contact Information
Primary
Frédéric VALLA
Frederic.valla@chu-lyon.fr
04 72 12 97 35
Backup
Florent BAUDIN
Florent.baudin@chu-lyon.fr
04 72 12 97 35
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 45
Treatments
Critically ill children ready for extubation
Children admitted to a paediatric intensive care unit, invasively ventilated and intubated, enterally fed and presenting with a clinical condition allowing for extubation. 45 children will be included.
Related Therapeutic Areas
Sponsors
Leads: Hospices Civils de Lyon

This content was sourced from clinicaltrials.gov