Effect of Electrical Stimulation of the Auricular Branch of the Vagus Nerve (ABVN) on Cervical Vagus Nerve Action Potentials Phase 2
The purpose of this study is to find out if we can gain access to the vagus nerve which is largely an internal nerve that controls stomach function. We hope to gain access to the internal vagus nerve by electrically stimulating the nerve around the external ear. If we can do this then we hope that this will help our treatment of patients with nausea and vomiting and disordered stomach function
• Healthy volunteers with no gastric symptoms or conditions (except due to COVID 19)
• Aged 18-80 years
• Willing to have electrodes placed in the external ear (ABVN arm)
• Willing to perform vagal activity maneuver (Vagal arm)
• Willing to have 1 tablespoon (15 ml) of blood drawn at 3 time points
• Gastroparesis subjects with a confirmed diagnosis of gastroparesis from a GI physician
• Have a formal diagnosis of gastroparesis or are seeing the GI physician for symptoms related to gastroparesis
• Aged 18-80 years
• Willing to have electrodes placed in the external ear (ABVN arm)
• Willing to perform vagal activity maneuver (Vagal arm)
• Willing to have 1 tablespoon (15 ml) of blood drawn at 3 time points