An Open-label Single Center, Proof of Concept Study Evaluating the Efficacy of Roflumilast Foam 0.3% in Pediatric Patients With Non-Segmental Vitiligo (NSV)

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

An open-label single center, proof of concept study evaluating the efficacy of Roflumilast foam 0.3% in pediatric subjects with Non-Segmental Vitiligo (NSV)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 18
Healthy Volunteers: f
View:

• Male or female subjects aged 2 years but less than 18 years

• Pediatric and adolescent subjects: Informed consent of parent(s) or legal guardian, and, if age appropriate, assent by the subjects, as required by local laws.

• Diagnosis of non-segmental vitiligo based on clinical history and dermatology examination for at least 3 months.

• Diagnosis of non-segmental vitiligo with the following:

‣ BSA affected \< 10% AND

⁃ At least 0.5% BSA affected on the face. AND

⁃ Pigmented hair within some of the areas of vitiligo on the face

• In good health as judged by the Investigator, based on the medical history, and dermatology examination.

• Subjects and parent(s)/legal guardian (s) are considered reliable and capable of adhering to the Protocol and visit schedule, according to the judgment of the Investigator.

Locations
United States
Texas
Derm Texas
RECRUITING
Dallas
Contact Information
Primary
Amanda Harvey, Study Coordinator
aharvey@derm-texas.com
2148456426
Time Frame
Start Date: 2025-08-01
Estimated Completion Date: 2026-06-15
Participants
Target number of participants: 20
Treatments
Experimental: Open-label single center, proof of concept study evaluating the efficacy of Roflumilast foam 0.3%
Related Therapeutic Areas
Sponsors
Collaborators: Arcutis Biotherapeutics, Inc.
Leads: Derm Texas, PLLC

This content was sourced from clinicaltrials.gov