Development of Motion-Model Ultrasound Localization Microscopy to Support Breast Cancer Diagnosis and Therapy Monitoring in Patients
The goal of this project is to adapt the super-resolution ultrasound imaging technology motion-model Ultrasound Localization Microscopy (mULM) to clinical application. In this exploratory patient study a scan protocol will be established to subsequently investigate whether mULM allows the assessment of the tumor response to neoadjuvant chemotherapy in participants with a primary breast cancer diagnosis as well as for the differentiation of benign and malignant breast tumors in participants with lesions of unknown dignity.
• written informed consent
• age ≥ 18 yrs
• histologically confirmed primary breast cancer including all intrinsic subtypes (study parts A and B)
• highly suspected primary breast cancer (study part C)
• treatment with neoadjuvant chemotherapy (study part B)
• persons who are legally competent and mentally able to follow the instructions of the study team