Post-Marketing Clinical Follow-Up Study to Confirm the Safety and Effectiveness/Performance of Motiva Flora® Tissue Expander in Staged Breast Reconstruction Surgery

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The Motiva Flora® Tissue Expander clinical study (hereafter Motiva Flora® TE study) is a 6-month, open-label, prospective, multicentre post-marketing follow-up study designed to confirm the Safety and Effectiveness/Performance of Motiva Flora® TE in breast reconstruction surgery. The study will include 136 women, planned for staged breast reconstruction, in 6 countries (Spain, Belgium, France, Costa Rica, Chile and Panama). Breast tissue expansion and the final breast implant will be performed using devices from the Motiva Flora® TE catalogue.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• The participant gives written informed consent.

• The participant is genetically female, aged 18 years or older.

• The participant needs tissue expansion as part of breast reconstruction treatment following mastectomy, which may include immediate reconstruction.

• The participant is in a suitable clinical condition to allow breast implant placement after tissue expander placement, at the discretion of the investigator.

• The participant has the physical and cognitive capacity to understand and follow the surgeon's recommendations.

• Complete radiotherapy at least 1 year before surgery.

• Partial or total decrease in tumour volume after radiotherapy.

• The participant is able and willing to comply with all study requirements including attending follow-up appointments.

• Participant with reasonable surgical risk.

• Participant with a history of non-metastatic breast cancer.

• Participant willing to undergo an MRI, CT scan and any other studies if required at surgeon discretion.

⁃ For substudy - MRI / CT - the following additional criteria apply:

⁃ \- Patient is willing to undergo one MRI and one CT anytime during the follow up

Locations
Other Locations
Chile
Centro de Cirugía Plástica y Reconstructiva. Dra. Viviana Spröhnle Hospital Regional de Rancagua
RECRUITING
Rancagua
Costa Rica
Centro Europeo de Cirugia
RECRUITING
San José
Panama
The Panama Clinic Complejo Hospitalario Pacific Center
RECRUITING
Panama City
Spain
Centro de Patología de la Mama
RECRUITING
Madrid
Hospital Gregorio Marañón
RECRUITING
Madrid
Contact Information
Primary
Catalina Solano
csolano@establishmentlabs.com
+506-83112829
Backup
Jorge Villalobos
jvillalobosa@establishmentlabs.com
+506-8839 6446
Time Frame
Start Date: 2020-12-14
Estimated Completion Date: 2026-07-15
Participants
Target number of participants: 136
Treatments
Other: Two-stage reconstruction
136 participants will undergo two-stage reconstruction
Related Therapeutic Areas
Sponsors
Leads: Establishment Labs

This content was sourced from clinicaltrials.gov