Breast Cancer Clinical Trials

• PRE-REGISTRATION: Age \>= 18 years and =\< 45 years of age

• PRE-REGISTRATION: Willingness to provide mandatory tissue specimens for correlative research at two timepoints.

• PRE-REGISTRATION: Had a live birth =\< 10 years prior to pre-registration

• PRE-REGISTRATION: Pre-menopausal according to patient report and/or clinical determination

• PRE-REGISTRATION: Provide written informed consent

• PRE-REGISTRATION: Ability to complete questionnaire(s) by themselves or with assistance

• PRE-REGISTRATION: Willingness to provide mandatory blood and urine specimens for correlative research

• REGISTRATION: Age \>= 18 years and =\< 45 years of age

• REGISTRATION: Registration for this study must be completed either =\< one (1) year after the qualifying pre-registration biopsy is performed for this study or =\< one (1) year after collection of the archived tissue (for those who did not have a pre-registration biopsy performed after pre-registration for this study)

• REGISTRATION: Hemoglobin \>= 9.0 g/dL (obtained =\< 30 days prior to registration)

• REGISTRATION: Platelet count \>= 100,000/mm\^3 (obtained =\< 30 days prior to registration

• REGISTRATION: Serum creatinine =\< 2.0 mg/dl (obtained =\< days prior to registration)

• REGISTRATION: Negative pregnancy test done =\< 14 days prior to registration

• REGISTRATION: Willing to use contraception while on treatment

• REGISTRATION: Provide written informed consent

• REGISTRATION: Ability to complete questionnaire(s) by themselves or with assistance

• REGISTRATION: Willingness to provide mandatory blood and urine specimens for correlative research

• REGISTRATION: Willing to return to enrolling institution for follow-up (during the active monitoring phase of the study)