Improving Exercise Capacity With a Tailored Physical Activity Intervention in Lymphoma and Breast Cancer Patients Undergoing Treatment

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral, Diagnostic test, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this research is to test whether participating in either a physical activity intervention or a series of educational classes will help to preserve exercise capability, heart function, brain-based activities (like memory), and quality of life. Participants will be randomized to 1 of 2 pathways: * First pathway consists of organized health workshops. These workshops are intended to provide information on topics such as proper nutrition, management of stress, sleep practices, and emphasis on a healthy lifestyle that may help the participants through cancer treatment. This pathway will also test whether stretching may help participants through cancer treatment. * Second pathway participants will take part in some unsupervised and some potentially supervised moderate activity sessions each week throughout participants' cancer treatment to take place either remotely or in person, depending on availability of facilities at the time visits are scheduled.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

⁃ To be considered eligible, participants must meet all of the following criteria:

• Individuals aged 18- 85 years

• Diagnosed with stage I-IV Hodgkin's or non-Hodgkin's lymphoma or stage I-III breast cancer

• Expected to receive an anthracycline based chemotherapeutic regimen or other potentially cardiotoxic cancer therapies (e.g. chemotherapy regimens \[anthracyclines, trastuzumab, rituximab\]), immuno-therapies (immune checkpoint inhibitors \[ICI's\]) or radiation (within 8 weeks of completion of radiation).29-31

• Ability to speak and understand English

• Capacity to walk at least 2 city blocks (\

⁃ .2 miles) on a flat surface

• Expected survival beyond 6 months.

• Must have an assistant that will help perform the home-based testing activities

Locations
United States
North Carolina
Wake Forest Baptist Comprehensive Cancer Center
RECRUITING
Winston-salem
Virginia
Virginia Commonwealth University
RECRUITING
Richmond
Contact Information
Primary
Study Coordinator
kristin.johnson@advocatehealth.org
336-758-3027
Backup
Pamela J. Grizzard
pamela.grizzard@vcuhealth.org
804-628-6234
Time Frame
Start Date: 2023-03-01
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 100
Treatments
Experimental: Physical Activity Intervention
Participants will have the ability to attend one to two training sessions per week and 1-2 sessions per week at home (the 4th level of our multi-level intervention) or the location site using the Trainerize application to deliver the exercise prescription.
Experimental: Healthy Living Intervention (Control Arm)
Participants randomized to the control arm will participate in organized health workshops. Each session will last 60 minutes and will be offered on location and virtually (e.g., Zoom) over 6 months. Participants will meet once a week for the first 4 weeks, biweekly for 3 months, and once a month for the last 2 months for a total of 12 sessions.
Sponsors
Leads: Wake Forest University Health Sciences
Collaborators: National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov

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