Respiratory Muscle Training During Breast Cancer Treatment: Effects on the Autonomic Nervous System and Cardiotoxicity

Status: Recruiting
Location: See location...
Intervention Type: Other, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This clinical trial evaluates whether home-based respiratory muscle training is useful for minimizing side effects in patients undergoing treatment for breast cancer. Over-activation of the nervous system during breast cancer treatment can result in heart- and lung-related side effects which have the potential to reduce a patient's quality of life. Aerobic exercise can help prevent the development of these side effects. However, engaging in regular aerobic exercise may be difficult for breast cancer patients who are actively undergoing treatment. Respiratory muscle training (RMT) involves a series of breathing and other exercises that are performed to improve the function of the respiratory muscles through resistance and endurance training. Home-based RMT may represent a more feasible approach for reducing side effects in patients undergoing treatment for breast cancer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Documented breast cancer and scheduled to receive adjuvant or neoadjuvant chemotherapy

• Age \>= 18 years old

• Cognitively capable of following direction and performing the intervention

• Able to speak, read and comprehend English language

• Understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

Locations
United States
New York
Roswell Park Cancer Institute
RECRUITING
Buffalo
Contact Information
Primary
ASK RPCI
askrpci@roswellpark.org
1-877-275-7724
Time Frame
Start Date: 2023-10-16
Estimated Completion Date: 2029-10-16
Participants
Target number of participants: 130
Treatments
Active_comparator: Group I (low resistance RMT Group)
Patients receive usual care for 12 weeks on study and a Respiratory Muscle training Device with small breathing resistance
Experimental: Group II (Moderate to highter resistance RMT)
Patients undergo RMT using a respiratory muscle training device with moderate to higher breathing resistance for 12 weeks on study.
Related Therapeutic Areas
Sponsors
Leads: Roswell Park Cancer Institute

This content was sourced from clinicaltrials.gov