Indoor Rowing as a Novel Exercise Therapy for Cardiovascular Rehabilitation in Middle-Aged and Older Breast Cancer Survivors Following Chemotherapy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

There are more than 3.8 million breast cancer survivors in the United States and cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect of a novel exercise intervention on cardiovascular rehabilitation in breast cancer survivors.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 80
Healthy Volunteers: f
View:

• diagnosis of primary invasive non-metastatic breast cancer, stages I-III

• female based on biological sex

• 40 to 80 years of age

• completed breast cancer treatment 6 to 24 months prior to study enrollment. Adjuvant endocrine therapy for breast cancer (e.g., ovarian suppression, SERMs, SERDs, AIs), CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed within 6 months prior to study enrollment and during study participation

• absence of contraindications to exercise or study participation

• study clinician approval

Locations
United States
Florida
Integrative Cardiovasculal Physiology Laboratory, University of Florida
RECRUITING
Gainesville
Contact Information
Primary
Demetra Christou, PhD
ddchristou@ufl.edu
352-294-1746
Time Frame
Start Date: 2024-02-26
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 72
Treatments
Experimental: Indoor Rowing
Research participants will be instructed how to use a Concept 2 RowErg and will be provided instruction on basic rowing skills for beginners. Exercise training will gradually progress to 50 min of moderate-intensity exercise, on 3 days per week, for 12 weeks.
No_intervention: Usual Care
Research participants in this group will have the opportunity to complete the supervised indoor rowing program after completing their post-intervention assessments.
Related Therapeutic Areas
Sponsors
Leads: University of Florida

This content was sourced from clinicaltrials.gov