A Multi-mode Thermophysical Immunotherapy Study for Breast Cancer Liver Metastases
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a single-center, parallel-controlled clinical study designed to evaluate the safety, efficacy and impact on systemic anti-tumor immunity of a multi-mode integrated ablation system for the treatment of breast cancer liver metastases.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Age 18-75 years, female gender;
• Pathologically confirmed breast cancer liver metastases, in patients who are unable to tolerate or refuse surgical resection;
• The number of lesions ≤ 3, with any single lesion diameter ≤ 4cm;
• At least an interval of 1 month since the last local treatment;
• Child-Pugh class A or B;
• ECOG PS score ≤2, with an expected survival of \>3 months.
Locations
Other Locations
China
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITING
Shanghai
Time Frame
Start Date: 2024-12-09
Estimated Completion Date: 2027-12
Participants
Target number of participants: 10
Treatments
Experimental: Multi-mode ablation
Subjects in this arm will receive image-guided multi-mode ablation.
Active_comparator: Conventional radiofrequency ablation
Subjects in this arm will receive image-guided radiofrequency ablation.
Related Therapeutic Areas
Sponsors
Leads: Ruijin Hospital