Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This study assesses the effect of hormone directed treatment for breast cancer on glucose metabolism.
Eligibility
Participation Requirements
Sex: Female
Healthy Volunteers: t
View:
• Post-menopausal women with hormone receptor positive breast cancer, ductal carcinoma in situ (DCIS), or with other high risk breast conditions. Post-menopause will be defined as women who experience 12 months of amenorrhea or have undergone bilateral salpingo-oophorectomy.
‣ 25 women who are planning to start or are within 6 months of starting treatment with aromatase inhibitors, after consultation in breast clinic and cancer center.
⁃ 25 women who will be starting Tamoxifen (comparative group)
⁃ 25 healthy post menopausal women will also be recruited.
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Clinical Trials Referral Office
mayocliniccancerstudies@mayo.edu
855-776-0015
Time Frame
Start Date: 2023-11-16
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 66
Treatments
Observational
Patients undergo blood sample collection, glucose testing, DEXA scan to measure body composition, complete a questionnaire and have their medical records reviewed on study.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic