Large Segmentation Radiotherapy±Deep Inspiratory Breath Hold for Left Sided Breast Cancer, A Real-World Study

Status: Recruiting
Location: See location...
Intervention Type: Device, Behavioral, Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The study is a single-center, prospective, non-randomized controlled study. The primary objective is to examine the clinical outcomes of utilizing Deep Inspiration Breath Hold (DIBH) in conjunction with hypo-fractionated radiotherapy for patients diagnosed with left-sided breast cancer with a particular focus on its potential to reduce the incidence of cardiac-related clinical and subclinical events.Participants will revieve large segmentation sadiotherapy ± DIBH for left breast cancer and be followed up to gather their clinical cardiac imformation.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• 18-70 years old, female, life expectancy \> 5 years

• ECOG 0, 1, 2 points

• Pathologically diagnosed with left breast cancer and underwent breast-conserving surgery or modified radical mastectomy

• The patient will receive radiation therapy to the entire breast or chest wall ± the lymphatic drainage area above and below the clavicle ± the lymphatic drainage area in the axilla.

• No prior neoadjuvant chemotherapy or breast reconstruction.

• No active cardiac disease, myocardial infarction, or congestive cardiac failure at baseline.

• Patients can hold their breath for at least 30 seconds after training

• Patients who can be followed up and agree to follow the plan.

• Sign the consent form.

Locations
Other Locations
China
Peking Union Medical College Hospital
RECRUITING
Beijing
Contact Information
Primary
Xiaorong Hou
hxr_pumch@163.com
+86 13811963013
Time Frame
Start Date: 2024-08-21
Estimated Completion Date: 2034-08-21
Participants
Target number of participants: 348
Treatments
Experimental: Surface guided radiation therapy (SGRT) combined with Deep Inspiration Breath Hold (DIBH) technique
Patients with left breast cancer treated with Surface guided radiation therapy (SGRT) combined with Deep Inspiration Breath Hold (DIBH) technique
Active_comparator: laser alignment combined with free breathing treatment
Patients with left breast cancer treated with traditional laser alignment with free breathing treatment
Related Therapeutic Areas
Sponsors
Leads: Peking Union Medical College Hospital

This content was sourced from clinicaltrials.gov

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