EVALUATION OF CANCER RISK BY MEASUREMENT OF CIRCULATING MUTATIONAL BURDEN IN CARRIERS OF A GENETIC PREDISPOSITION
Status: Recruiting
Location: See location...
Intervention Type: Genetic
Study Type: Observational
SUMMARY
Cancer-free women with a hereditary predisposition to breast and/or ovarian cancer
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 30
Maximum Age: 50
Healthy Volunteers: t
View:
• Female participant
• Participant undergoing oncogenetic follow-up at the Centre François Baclesse
• Participant belonging to a pair of related biological siblings
• Within the sibling pair, one participant is a carrier of a hereditary predisposition linked to a BRCA1/2 mutation (case), and the other participant is not a carrier (control).
• Participant between 30 and 50 years of age
• Participant affiliated to a social security scheme
• Participant having given her consent to participate by signing an informed consent form prior to any specific study-related procedure.
Locations
Other Locations
France
Centre François Baclesse
RECRUITING
Caen
Contact Information
Primary
Louise May THIBAUT, Medical Doctor
lm.thibaut@baclesse.unicancer.fr
0231455050
Time Frame
Start Date: 2025-07-04
Estimated Completion Date: 2027-12-30
Participants
Target number of participants: 30
Treatments
Case group
participant with a hereditary predisposition linked to a BRCA1/2 mutation (case)
Control group
participant not carrying a hereditary predisposition linked to a BRCA1/2 mutation (control) participant from the same sibling as the carrier participant (sister)
Related Therapeutic Areas
Sponsors
Leads: Centre Francois Baclesse