Application of CfDNA Methylation Detection in Auxiliary Diagnosis of Breast Cancer
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to construct an auxiliary diagnostic model for breast cancer by methylation markers. The study will collect blood and tissue samples from participants with breast cancer and benign disease for whole-genome methylation sequencing. It will screen methylation markers and develop a methylation auxiliary diagnosis model to distinguish between breast cancer and non-cancer.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 75
Healthy Volunteers: f
View:
• With confirmed pathological diagnosis and molecular subtyping results
• Ability to provide a written informed consent
Locations
Other Locations
China
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
RECRUITING
Beijing
Time Frame
Start Date: 2025-03-15
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 200
Treatments
Cancer Arm
Participants with breast cancer from which a tumor tissue will be collected. Participants with new diagnosis of breast cancer from which a blood sample will be collected.
Benign Diseases Arm
Participants with breast benign diseases from which a tissue will be collected. Participants with breast benign diseases from which a blood sample will be collected.
Related Therapeutic Areas
Sponsors
Collaborators: Chinese Academy of Medical Sciences
Leads: Geneplus-Beijing Co. Ltd.