Lyon Initiative for the Mobile Demedicalized Initiation of Lung Cancer Screening

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral, Diagnostic test, Other
Study Type: Observational
SUMMARY

Lung cancer screening using low-dose CT (LDCT) has been shown to reduce mortality in high-risk populations. In 2022, the French National Cancer Institute (INCa) issued guidelines recommending screening for individuals aged 50-74 with a history of heavy smoking, including current smokers or those who quit less than 15 years ago. A national pilot program (IMPULSION) will be launched in 2025. Lung cancer incidence is strongly correlated with socioeconomic status, yet underserved populations remain difficult to engage in screening programs. Mobile health units using a reach-out strategy have demonstrated effectiveness in other countries (UK, Brazil, USA). In France, this approach has been used for breast cancer screening via mobile mammography units. The MobILYAD project aims to compare two screening modalities- a mobile demedicalized unit (CT-equipped van with trained nurses) and a conventional hospital-based unit- to assess the effectiveness of mobile screening in reaching socially disadvantaged populations.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 75
Healthy Volunteers: t
View:

• Persons aged over 50 and under 75 (74 years of age or older).

• Active smokers or former smokers who quit less than 15 years ago.

• Persons whose consumption is estimated at 20 packs/year or more, down to ≥15 cigarettes/day for a duration of consumption of ≥25 years and up to ≥10 cigarettes/day for ≥30 years, which takes into account the predominance of duration of consumption over quantity consumed in the risk of lung cancer. A pack-year corresponds to the consumption of one pack of 20 manufactured cigarettes per day for one year. A multiplier coefficient will be taken into account depending on the mode of consumption: Rolled cigarettes: 2; Cigarillos: 3; Cigars: 4; Pipes: 2.5; Hookahs: 25.

• Persons affiliated with social security. - Person having signed their consent to participate in the study after having received full information about it, including the risks associated with participation.

Locations
Other Locations
France
Centre de dépistage mobile - Hôpital Lyon Sud
RECRUITING
Pierre-bénite
Service de Pneumologie Centre de dépistage non mobile - Hôpital Lyon Sud
RECRUITING
Pierre-bénite
Contact Information
Primary
Sébastien COURAUD, Pr
sebastien.couraud@chu-lyon.fr
04 78 86 44 01
Backup
Julie DE-BELMONT
Julie.de-bermont@chu-lyon.fr
0478866698
Time Frame
Start Date: 2025-06-12
Estimated Completion Date: 2028-09
Participants
Target number of participants: 4312
Treatments
Mobile Screening Group
Participants receiving lung cancer screening via a mobile unit (truck) operated by trained nurses. This includes spirometry, blood pressure measurement, blood cholesterol testing, low-dose CT scan, and optional biospecimen collection.
Non-Mobile Screening Group
Participants receiving the same screening procedures at a fixed hospital-based site (Lyon Sud), with possible involvement of medical or non-medical staff depending on availability.
Sponsors
Leads: Hospices Civils de Lyon

This content was sourced from clinicaltrials.gov