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Optimal Mammography View Sequencing in Women With a History of Breast Cancer Undergoing Surveillance Mammography

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This prospective, single-centre, parallel-group randomised controlled trial evaluates the optimal sequencing of mammography views in women with a history of breast cancer undergoing surveillance mammography. Women treated with breast-conserving surgery within the previous five years will be randomised 1:1:1:1 to one of four mammography view sequencing groups. The primary objective is to compare patient-reported pain and satisfaction across sequencing groups. Secondary objectives include comparison of image quality (PGMI scoring), compression force, and breast thickness. A total of 400 participants will be enrolled at Beaumont Hospital Breast Care Centre over 2.5 years.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Female patients aged 18 years or older History of breast cancer treated with breast-conserving surgery (wide local excision) Undergoing first annual surveillance mammogram following completion of surgery and radiotherapy Within five years of breast cancer treatment May have history of whole-breast or partial-breast radiotherapy May have history of axillary surgery Able and willing to provide informed consent

Locations
Other Locations
Ireland
Beaumont RCSI Cancer Centre
RECRUITING
Beaumont
Contact Information
Primary
Prof Nuala Healy
nualahealy@rcsi.ie
+35318093000
Time Frame
Start Date: 2026-02-24
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 400
Treatments
Experimental: Untreated MLO First
Participants undergo surveillance mammography in the following sequence: Untreated mediolateral oblique (MLO), Treated MLO, Untreated craniocaudal (CC), Treated CC.
Experimental: Untreated CC First
Participants undergo surveillance mammography in the following sequence: Untreated CC, Treated CC, Untreated MLO, Treated MLO.
Experimental: Treated MLO First
Participants undergo surveillance mammography in the following sequence: Treated MLO, Untreated MLO, Treated CC, Untreated CC.
Experimental: Treated CC First
Participants undergo surveillance mammography in the following sequence: Treated CC, Untreated CC, Treated MLO, Untreated MLO.
Related Therapeutic Areas
Sponsors
Leads: Royal College of Surgeons, Ireland

This content was sourced from clinicaltrials.gov