Intra-operative Radiotherapy After Breast-conversing Surgery in Treating Women With Ductal Carcinoma in Situ Breast Cancer

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Whether the patients with low grade ductal carcinoma in situ breast cancer should accept radiationtherapy is uncertain.Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Tumor diameter \< 5 cm

• Low grade ductal carcinoma in situ

• Candidate for breast-conserving surgery

• Must have undergone lumpectomy with negative margins or minimal margin involvement

• Currently undergoing re-excision of the biopsy cavity and/or sentinel lymph node biopsy or axillary lymph node dissection

• No evidence of metastatic disease

• Informed consent

Locations
Other Locations
China
Guangdong Academy of Medical Sciences
RECRUITING
Guangzhou
Contact Information
Primary
Liao Ning, MD,PhD
+86 83827812
Time Frame
Start Date: 2014-10
Estimated Completion Date: 2026-06
Participants
Target number of participants: 222
Treatments
No_intervention: Without Radiotherapy
Patients just accept breast-conversing surgery without radiotherapy.
Experimental: Intraoperative Radiotherapy
Boost with 20 Gy during BCS, EBRT with 46-50 Gy
Related Therapeutic Areas
Sponsors
Leads: Liao Ning

This content was sourced from clinicaltrials.gov