Vision and Balance Changes After Bilateral Implantation of Toric Versus Non-Toric Intraocular Lenses in Cataract Patients With Astigmatism

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Cataracts are the major cause of blindness in the world. Cataract surgery, being the most performed surgery in the world today, provide correction by extracting the natural lens from its capsular bag and replaced by an artificial intraocular lens (IOL) implantation. In the UK, almost all patients undergoing cataract surgery by the NHS are given monofocal intraocular lenses (IOLs) which do not correct corneal astigmatic error. It is estimated that around 20% of the population has over 1.50DC of corneal astigmatism. Uncorrected astigmatism not only increase spectacle dependency and reduce quality of life post surgically, but it also adversely affects the overall economic costs. Specialised toric IOLs offer the opportunity to correct pre-existing corneal astigmatism. Previous work has shown a link between reduced vision and balance or mobility. Full correction of refractive error may have greater impact on lifestyle than previously thought.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 75
Healthy Volunteers: f
View:

• bilateral significant corneal astigmatism \>1.0D

• on waiting list for bilateral cataract surgery in NHS

Locations
Other Locations
United Kingdom
Royal Eye Infirmary
RECRUITING
Plymouth
Contact Information
Primary
Sherrie T Choy, MSc
sherrie.choy@plymouth.ac.uk
07903692005
Time Frame
Start Date: 2024-01-12
Estimated Completion Date: 2025-07-31
Participants
Target number of participants: 140
Treatments
Active_comparator: Toric Intraocular lens
Toric intraocular lens- AT TORBI® 709M, to be implanted bilaterally in the cataract surgery to correct astigmatism at the same time.
Active_comparator: Monofocal intraocular lens
Standard monofocals IOLs- Zeiss CT ASPHINA 409/509M, to be implanted bilaterally in the standard NHS cataract surgery without correcting the astigmatism.
Related Therapeutic Areas
Sponsors
Leads: University of Plymouth
Collaborators: Carl Zeiss Meditec AG, Glasgow Caledonian University, University of St Mark and St John Plymouth, University Hospital Plymouth NHS Trust

This content was sourced from clinicaltrials.gov