Single Center Post-Market Clinical Follow-Up (PMCF) Investigation for Assessing the Visual Performance of Hanita Lenses Intensity SL IOL in Comparison to Alcon Panoptix IOL

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to compare the visual performance between Intensity SL IOL and Panoptix IOL in men and women diagnosed with cataract who require cataract surgery procedure that meet the inclusion criteria and provide written informed consent will be enrolled in the study. The main questions it aims to answer are: 1. To show non-inferiority in binocular distance corrected visual acuity for far, intermediate and near distances after Trifocal IOL implantation. 2. To show non-inferiority in the Defocus Curve measurement 3. To show non-inferiority in Contrast Sensitivity measurement 4. To show non-inferiority in patient satisfaction Participants will attend a total of 10 study visits: 1 preoperative visit, 2 operations and 7 postoperative visits.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Capability to understand and sign an IRB approved informed consent form and privacy authorization

• Age over 18 on the screening day

• Patients with bilateral age-related cataracts and planned bilateral cataract phacoemulsification combined Intraocular Lens implantation;

• Calculated IOL power is within range 15-30 Diopter (approximate range of axial lengths: 21-25.5mm)

• Normal corneas with corneal astigmatism below following value, measured by Biometer

‣ 1 D if with-the-rule (steep axis is vertical, between 60-120⁰)

⁃ 0.4 D if against-the-rule (steep axis is horizontal, 0-30⁰ or 150-180⁰)

⁃ 0.7 D if oblique (not one of the cases above)

• Post-operative best corrected distance visual acuity expected to be 0.3 logMAR or lower

• Patient motivated for trifocal IOL after screening by surgeon, willing and able to conform to the study requirements

• Fundus visualization is possible

• Absence of retinal or optic nerve diseases

• Clear intraocular media other than cataract

• When scheduling the first surgery, the patient shall commit to:

‣ Availability for the follow-up visits - 1 day, 1 week and 1 month after the first surgery

⁃ Availability for the second surgery - one week to two months after the first surgery

⁃ Availability for the follow-up visits - 1 day, 1 week, 1 month and 3 months after the second surgery

Locations
Other Locations
Germany
Universitäts-Augenklinik Heidelberg International Vision Correction Research Centre (IVCRC)
RECRUITING
Heidelberg
Contact Information
Primary
Raquel Willrich Amroussi, M.A
raquel.willrichamroussi@med.uni-heidelberg.de
49 6221 56-36849
Time Frame
Start Date: 2023-07-13
Estimated Completion Date: 2026-03-01
Participants
Target number of participants: 58
Treatments
Active_comparator: Intensity SL IOL
29 patients will be implanted bilaterally with Intensity SL IOL
Active_comparator: Panoptix IOL
29 patients will be implanted bilaterally with PanOptix IOL
Related Therapeutic Areas
Sponsors
Leads: Hanita Lenses

This content was sourced from clinicaltrials.gov