EPIC: Evaluation of the Postoperative Cataract Surgery Outcomes in Patients With Prior Corneal Laser Vision Correction Implanted With the CT LUCIA Intraocular Lens Protocol GPAS-SAS-023-4

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY

This is a prospective, Phase IV, post-approval observational study evaluating postoperative outcomes in patients with a history of myopic corneal laser vision correction (LVC) undergoing bilateral cataract surgery with implantation of the CT LUCIA 621P intraocular lens (IOL). Up to 30 subjects (60 eyes) will be enrolled across up to three U.S. investigational sites. The study will assess visual and refractive outcomes, including biometry, manifest refraction, and patient-reported visual function over a 3-month follow-up period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Be at least 18 years of age or older.

• Previous cornea LVC surgery performed at least 1 year before the implantation of the CT LUCIA 621P IOL, such as Laser-Assisted Intrastromal Keratomileusis (LASIK), Laser-Assisted Subepithelial Keratectomy (LASEK), Photorefractive Keratectomy (PRK) or Small Incision Lenticule Extraction (SMILE) for mild to moderate myopia, with or without astigmatism (up to, but not including, -6.0 D sphere in any meridian for myopic ablations.

• Presenting for planned bilateral cataract extraction with in-the-bag posterior chamber IOL implantation, via phacoemulsification with or without femtosecond laser assisted cataract surgery (FLACS). Astigmatism management techniques, such as Astigmatic Keratotomy (AK), may be utilized during cataract surgery to target a predicted postoperative cylinder less than 0.75 D.

• Clear intraocular media other than cataract (i.e., no hyphema, vitreous hemorrhage).

• No visual acuity limiting corneal or retinal pathologies.

• Able to and having provided written informed consent and a signed Health Insurance Portability and Accountability Act (HIPAA) form.

• Availability, willingness, ability, and sufficient cognitive awareness to comply with study examination procedures and the schedule for study visits and evaluations.

Locations
United States
Texas
Berkeley Eye Center
RECRUITING
Sugar Land
Virginia
Piedmont Eye Center
RECRUITING
Lynchburg
Contact Information
Primary
Henry Heering
henry.heering@zeiss.com
949-293-0520
Time Frame
Start Date: 2025-07
Estimated Completion Date: 2026-09
Participants
Target number of participants: 30
Treatments
CT LUCIA 621P IOL Implantation Group
Subjects with prior myopic corneal laser vision correction undergoing bilateral cataract surgery implanted with the CT LUCIA 621P intraocular lens. All subjects will be followed prospectively to assess postoperative visual and refractive outcomes.
Related Therapeutic Areas
Sponsors
Leads: Carl Zeiss Meditec AG

This content was sourced from clinicaltrials.gov