Cognitive and Motor Function Examination in Patients With Urea Cycle Disorders (UCD) During a Driving Task Using Functional Near Infrared Spectroscopy (fNIRS)
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This study is being done to understand how the brain works while people with urea cycle disorder (UCD) perform driving tasks that range from easy to difficult and to look at how that compares to traditional tests of thinking and attention.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Maximum Age: 40
Healthy Volunteers: t
View:
• Individuals 16 to 40 years with molecular or biochemical confirmation of a urea cycle disorder.
• Healthy individuals will serve as an age and sex matched comparison group. Active driver's license for at least 6 months
• Read and understand English. as the tasks have not been validated in other languages
• IQ \>=70.
Locations
United States
Tennessee
St. Jude Children's Research Hospital
RECRUITING
Memphis
Contact Information
Primary
Jean Laboe, RN
jean.laboe@stjude.org
901-595-1693
Time Frame
Start Date: 2026-07-20
Estimated Completion Date: 2032-08
Participants
Target number of participants: 60
Treatments
UCD group
Participants with urea cycle disorders (UCD) who meet the Eligibility Criteria and consent to participate
Control group
Healthy controls who meet the Eligibility Criteria and consent to participate
Related Therapeutic Areas
Sponsors
Leads: St. Jude Children's Research Hospital