Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients

Status: Recruiting
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and culture examinations as part of the diagnostic process, will be sent for examination of the characteristics of the urinary microbiome and metabolome (UMM) before and after treatment.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult women over 18 years of age

• Written consent to participate in the study

• Willingness to undergo OAB evaluation and treatment according to the protocol

• OAB symptoms lasting longer than 3 months

• At least 3 episodes of severe urgency with or without urge incontinence within 3 days documented by voiding diary

• OAB symptom score V8 questionnaire ≥ 8

Contact Information
Primary
Jiří Hynčica
jiri.hyncica@fno.cz
0042059737
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 80
Treatments
Overactive Bladder Patients
Patients with the symptoms of overactive bladder will be enrolled in this study group
Related Therapeutic Areas
Sponsors
Collaborators: Institute of Microbiology of the Czech Academy of Sciences, University Hospital Bulovka, Thomayer University Hospital
Leads: University Hospital Ostrava

This content was sourced from clinicaltrials.gov