Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The objectives are to evaluate whether variations in vaginal and/or urinary and/or fecal microbiome predispose postmenopausal women to recurrent cystitis. This will be explored using comparison of microbiome profiles between those with recurrent UTI compared to age-matched women without recurrent UTI.
Eligibility
Participation Requirements
Sex: Female
Healthy Volunteers: t
View:
• Menopausal status
• Two or more documented, culture-positive infections in the last six months or ≥3 infections in the last year Patients' exclusion criteria
• Neurogenic bladder condition
• Known immunodeficiencies
• Usage of antibiotics or probiotics within the previous month
• Known renal calculi or anatomic malformations
• Menopausal status
• Sterile urine cultures, normal urinalysis, and negative sexually-transmitted PCR urine assay
Locations
Other Locations
Israel
Hadassah Medical Center
RECRUITING
Jerusalem
Contact Information
Primary
Ahinoam Lev-Sagie, MD
levsagie@netvision.net.il
97225844000
Time Frame
Start Date: 2021-08-01
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 40
Treatments
Recurrent Urinary tract infection
Menopausal women, with two or more documented, culture-positive infections in the last six months or ≥3 infections in the last year
Healthy controls
Menopausal women, without prior history of UTIs or other urologic abnormalities.
Related Therapeutic Areas
Sponsors
Leads: Hadassah Medical Organization