Function of Tamsulosin in Older Males Undergoing Surgery with Indwelling Catheter: a Randomized Clinical Trial

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study is being done to answer the question: What is the impact of a medication called tamsulosin (also called Flomax) on the rate of postoperative urinary retention (POUR) and catheter-associated urinary tract infection (UTI)? One of the most common complications following surgery and associated with Foley catheters is post-operative urinary retention (POUR) after the catheter is removed. This is defined as being unable to urinate spontaneously within 8 hours following the removal of the indwelling Foley catheter (the catheter that sits in your bladder to drain urine after surgery). When this happens, it requires intermittent straight catheterization of the bladder (placing a temporary catheter in the bladder to drain the buildup of urine), which can cause a lot of discomfort and anxiety, as well as increase the risk of catheter-associated urinary tract infection (CAUTI).

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 50
Healthy Volunteers: f
View:

• Planned for elective surgery for any reason (benign, malignant, or indeterminate lesion) with either an open or minimally invasive approach (hepatobiliary, pancreatic, and colorectal operations)

• Male and age ≥50 years

• Deemed physically fit for surgery

Locations
United States
Georgia
Emory Saint Joseph's Hospital
RECRUITING
Atlanta
Emory University Hospital (EUH)
RECRUITING
Atlanta
Emory University Hospital Midtown
RECRUITING
Atlanta
Contact Information
Primary
Kenneth Cardona, MD
kcardon@emory.edu
404-686-3203
Time Frame
Start Date: 2024-02-26
Estimated Completion Date: 2026-02
Participants
Target number of participants: 212
Treatments
Experimental: Tamusolin
Participants will receive tamsulosin postoperatively for two days.
Other: Control Group
Participants will be randomized to the standard of care, with no medication given.
Sponsors
Collaborators: ABRAHAM J & PHYLLIS KATZ FOUNDATION
Leads: Emory University

This content was sourced from clinicaltrials.gov