Uterine Fibroids Clinical Trials

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Temporary Uterine Tourniquet Application Versus Local Myometrial Epinephrine Injection During Laparoscopic Myomectomy

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

While both local vasoconstrictors and tourniquet application are recognized methods for blood loss control, there is a paucity of head-to-head randomized controlled trials directly comparing these two distinct approaches in laparoscopic myomectomy. Existing data often compare these methods to no intervention or to other less common techniques. A direct comparison is essential to determine which method offers superior hemostasis with an acceptable safety profile in the laparoscopic setting. This study aims to address this gap in the literature.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• Female patients aged 18-45 years.

• Diagnosed with symptomatic uterine leiomyomas requiring laparoscopic myomectomy.

• Presence of at least one myoma with a diameter ≥3 cm and ≤10 cm.

• Patients with up to 3 myomas (to standardize surgical complexity).

• Preoperative hemoglobin level ≥10 g/dL.

• Ability to provide informed consent.

Locations
Other Locations
Egypt
Minia advanced laparoscopy unit
RECRUITING
Minya
Time Frame
Start Date: 2026-04-20
Estimated Completion Date: 2027-01-20
Participants
Target number of participants: 74
Treatments
Active_comparator: Temporary Uterine Tourniquet Application
Active_comparator: Local Myometrial Epinephrine Injection
Related Therapeutic Areas
Sponsors
Leads: Minia University

This content was sourced from clinicaltrials.gov