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Study of CCR Receptor Overexpression in Fetal Microchimeric Cells: Proof of Concept Before a Potential Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to describe the transcriptomic profile of foetal cells in post-partum and more specifically to determine which chemokine receptors are overexpressed in foetal cells in post-partum women with wounds To do so, the investigators will isolate foetal cells from the peripheral blood of healthy controls post partum women as well as from post partum women with skin ulcers and then perform RNA sequencing.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: t
View:

⁃ Common criteria :

• Adult women,

• Post-partum: having been pregnant for any length of time,

• Having signed a free and informed consent form,

• Primiparous or multiparous,

• Affiliated to a health insurance

⁃ Patients :

⁃ \- Patients with a venous, diabetic or sickle cell ulcer, or mixed ulcer

⁃ Control group patients :

• Volunteers,

• Age-matched,

• Without skin ulcers.

⁃ There are no specific criteria for children.

Locations
Other Locations
France
Dermatology unit - Cochin Hospital - APHP
RECRUITING
Paris
Contact Information
Primary
Sélim ARACTINGI, MD, PHD
selim.aractingi@aphp.fr
00 33 1 58 41 18 13
Backup
Marie Benhammani-Godard
marie.godard@aphp.fr
00 33 1 58 41 11 90
Time Frame
Start Date: 2024-02-06
Estimated Completion Date: 2027-02-01
Participants
Target number of participants: 160
Treatments
Other: Patients
Patients who have had at least one pregnancy and have a venous ulcer, diabetic ulcer or sickle cell ulcer
Other: Patient Controls group
Post-partum women of the same age but without wounds.
Other: Children
Related Therapeutic Areas
Sponsors
Collaborators: URC-CIC Paris Descartes Necker Cochin
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov