Efficacy of High-Intensity Laser Therapy in the Management of Venous Leg Ulcers: A Randomized Controlled Trial
This randomized controlled trial will evaluate the effects of high-intensity laser therapy on wound healing in patients with venous leg ulcers. Participants will be randomly assigned to receive either laser therapy plus standard care or standard care alone. The laser therapy will be administered 3 times per week for 8 weeks or until ulcer closure. The primary outcome is proportion of participants with complete ulcer closure.
• Male or female patients aged 18 years up to 65 years.
• Presence of a venous leg ulcer, confirmed by clinical examination and Doppler ultrasound (venous reflux \> 0.5 seconds).
• Ulcer size between 1 cm² and 20 cm² at screening.
• Ulcer duration of at least 4 weeks but not more than 12 months.
• Ankle-brachial index (ABI) ≥ 0.8, assessed by Doppler ultrasound.
• Willing and able to provide informed consent and comply with study procedures.