Evaluation of the Effects of Continuous Anterior Chest Compression on Ventilation/Perfusion Ratios and Hemodynamics in SDRA

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Objective: Primary outcome : To evaluate the effects of CCAC on ventilation/perfusion ratios during moderate to severe ARDS. Secondary outcome : To evaluate the effects of CCAC on hemodynamics : left heart morphology, systolic and diastolic function, cardiac output, right heart morphology, systolic function, pulmonary hypertension, volemia. Method In patient with moderate to severe ARDS, CACC is performed manually and the pressure applied will be maintained between 60 and 80 cmH2O. Electrical impedance tomography of ventilation and perfusion will be used for the measurement of the percentage of areas with normal VA/Q ratios, areas of shunt and areas of dead space effect. Left heart morphology, systolic and diastolic function, cardiac output, right heart morphology, systolic function, pulmonary hypertension, volemia will be evaluated by using echocardiography.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years

• ARDS moderate to severe according to the Berlin criteria

• Patient receiving continuous sedation and curarization

• Free and informed consent from the patient or family member

Locations
Other Locations
France
Henri Mondor hospital
RECRUITING
Créteil
Contact Information
Primary
Labedade
Pascale.labedade@aphp.fr
0145178506
Time Frame
Start Date: 2023-02-28
Estimated Completion Date: 2025-05-30
Participants
Target number of participants: 20
Treatments
Experimental: Patient with moderate to severe ARDS under sedation andcontinuous curarization
Patient with moderate to severe ARDS under sedation andcontinuous curarization
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov

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