Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial Pressure
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
Dexmedetomidine is a potent alpha-2 adrenergic receptor agonist. In addition, dexmedetomidine-induced stimulation of the postsynaptic alpha-2 adrenergic receptor on the cerebral blood vessels can cause cerebral vasoconstriction and decrease cerebral blood flow
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 70
Healthy Volunteers: f
View:
• ASA I-II Patients scheduled for elective robot-assisted laparoscopic prostatectomy
Locations
Other Locations
Egypt
facility of medicine Cairo university
RECRUITING
Cairo
Contact Information
Primary
Amr Samir Wahdan
amrwahdan@kasraliny.edu.eg
+201001422499
Time Frame
Start Date: 2024-04-12
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 60
Treatments
Experimental: Group (D)
Dexmedetomidine with Mannitol
Experimental: Group (M)
Mannitol only
Related Therapeutic Areas
Sponsors
Leads: Cairo University