Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients: a Multicentre Cluster Randomised Controlled Trial (PETS)

Status: Recruiting
Location: See all (9) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Hospital acquired thrombosis describes blood clots that form in the legs and lungs after someone is treated in hospital. Clots in the leg can cause swelling, pain and other problems. If a clot in the leg travels to the lungs, it may be life threatening. Having surgery increases the risk of developing blood clots. People having short-stay surgery (who either go home the same day or who stay overnight but go home shortly afterwards) are at a much lower risk of developing a blood clot than those who stay in hospital for longer. These low-risk people are often given elastic stockings (which squeeze the leg muscles) to reduce the chance of a blood clot. The risks of wearing the stockings are low but they can be uncomfortable. In the UK, there are over a million short stay surgeries performed each year and most of these people are given elastic stockings to wear. Stockings cost the NHS a lot of money and it remains unknown if they work. This study will investigate if it is worthwhile to continue using elastic stockings in people having surgery where the risk of developing blood clots is low. Adults (over 18-years) who are at low risk of developing blood clots (assessed using a nationally recognised tool) will be included.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 59
Healthy Volunteers: t
View:

• Adults (18-59 years of age) scheduled to undergo a surgical procedure with a hospital stay \<48 hours

• Individuals assessed as being at low-risk of developing VTE as per the DHRA Tool (i.e. no assessed thrombosis risk factors / scoring 0)

Locations
Other Locations
United Kingdom
Barnsley Hospital NHS Foundation Trust
RECRUITING
Barnsley
Frimley Health NHS Foundation Trust
RECRUITING
Camberley
Queen Victoria Hospital NHS Foundation Trust
RECRUITING
East Grinstead
Imperial College Hospital NHS Foundation Trust
RECRUITING
London
South Tees Hospitals NHS Foundation Trust
RECRUITING
Middlesbrough
The Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITING
Newcastle Upon Tyne
Sherwood Forest Hospital NHS Foundation Trust
RECRUITING
Nottingham
North Tees and Hartlepool NHS Foundation Trust
RECRUITING
Stockton-on-tees
Somerset NHS Foundation Trust
RECRUITING
Taunton
Contact Information
Primary
Sarah Whittley
s.whittley@imperial.ac.uk
0203 311 7371
Time Frame
Start Date: 2022-09-08
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 21472
Treatments
No_intervention: Control - No graduated compression stockings
In those centres randomised to the control arm, participants will not receive Graduated Compression Stockings (GCS).
Experimental: Intervention - The provision of graduated compression stockings
Centres randomised to the intervention arm, which is the current standard of care, will consist of participants receiving Graduated Compression Stockings (GCS). Clinical staff (e.g. theatre support workers) will issue stockings to all patients who are scheduled to undergo short-stay surgery. Participants will be instructed to wear their stockings just before undergoing the surgical procedure and to remove the stockings as soon as they are ambulant (i.e. after the procedure).
Related Therapeutic Areas
Sponsors
Collaborators: Universidad de Granada, University of Edinburgh
Leads: Imperial College London

This content was sourced from clinicaltrials.gov