Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For Venous Thromboembolism (VTE) Following Total Joint Arthroplasty - A Multi-center Prospective Randomized Control Trial.
Who is this study for? Patients with Venous Thromboembolism
What treatments are being studied? Aspirin
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
This research study is attempting to answer the question of whether 81 mg aspirin once daily is as effective as 81 mg aspirin twice daily in preventing blood clots after total joint replacement surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:
• \> 18 years of age
• Planning to undergo a primary total hip or knee arthroplasty
Locations
United States
Florida
University of Miami Hospital
RECRUITING
Miami
Contact Information
Primary
Ramakanth Yakkanti, MD
ramakanth.yakkanti@jhsmiami.org
502-689-3127
Time Frame
Start Date: 2021-03-01
Estimated Completion Date: 2026-03-01
Participants
Target number of participants: 5478
Treatments
Experimental: Treatment Once Daily
Participant receives 81 mg aspirin taken once daily beginning the night before surgery and up to 28 days post surgery.
Active_comparator: Treatment Twice Daily
Participant receives 81 mg aspirin taken twice daily (one in the morning and one at night) beginning at the night before surgery and up to 28 days post surgery.
Related Therapeutic Areas
Sponsors
Leads: University of Miami