Venous Thromboembolism (VTE) Clinical Trials

Find Venous Thromboembolism (VTE) Clinical Trials Near You

AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Hospital-acquired blood clots (HA-VTE) are the leading cause of death in hospitalized patients in the US. Each year, about 900,000 people get blood clots, costing between $7 and $10 billion in medical expenses. HA-VTE is the second leading cause of long-term disability and causes significant health issues and deaths in both adults and children. About 1 in 3 people who get blood clots experience long-term complications. Reducing HA-VTE is a major challenge. This study will test a new AI method to predict and prevent HA-VTE. The goal is to see if this AI tool can reduce the number of HA-VTE cases in the Vanderbilt Health System, which includes both urban and rural hospitals. The AI tool, called VTE-AI, calculates a risk score without needing input from doctors. It will suggest reconsidering blood clot prevention measures for patients who don't have them ordered and have no reasons to avoid them. This suggestion will be made after admission and daily during the hospital stay. Currently, doctors manually calculate a risk score and choose a prevention option. This study will compare the effectiveness of the AI tool against the current manual method in reducing HA-VTE cases. The study will randomly assign half of the patients to use the AI tool and the other half to the standard manual method.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Inpatient admission to Vanderbilt Adult Hospital, Vanderbilt Tullahoma Harton Hospital, Vanderbilt Bedford County Hospital, or Vanderbilt Wilson County Hospital

Locations
United States
Tennessee
Vanderbilt University Medical Center
RECRUITING
Nashville
Time Frame
Start Date: 2025-12-17
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 2236
Treatments
Experimental: Interventional
Hospitalizations randomized to receive risk model-driven CDS
No_intervention: Standard of Care
Hospitalizations randomized to receive Standard of Care in a given clinical setting
Related Therapeutic Areas
Sponsors
Leads: Vanderbilt University Medical Center

This content was sourced from clinicaltrials.gov