Treatment of Peri-implant Mucositis by Non-surgical Debridement and Additional Application of a Spermidine-based Gel
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of the study is to evaluate the potential of a spermidine-based topical gel as an adjuvant to non-surgical treatment of peri-implant mucositis. After a meticulous selection, patients will be randomly assigned to Test (spermidine gel + non-surgical debridement) or Control group (non-surgical debridement).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: t
View:
• Age ≥ 18 years;
• Non-smokers and smokers ( ≤ 10 cigarettes/day);
• Presence of at least 1 implant in mucositis, clinically and radiographically detected;
• The implant in mucositis (tissue-level or bone-level) must support a fixed prosthetic device (single crown), cemented or screwed.
Locations
Other Locations
Italy
University of Naples Federico II
RECRUITING
Naples
Contact Information
Primary
Luca Ramaglia
luca.ramaglia@unina.it
+393476912911
Time Frame
Start Date: 2023-07-01
Estimated Completion Date: 2024-06-01
Participants
Target number of participants: 20
Treatments
Experimental: Spermidine Group
Mechanical therapy (NSMD) will be performed by means of an ultrasonic scaler with a plastic tip. Finally, the spermidine-based gel will be applied in the peri-implant sulcus using a blunt-tipped needle.
Active_comparator: NSMD Group
Control group will be treated only through a non-surgical mechanical therapy with curettes or scaler peek tips.
Related Therapeutic Areas
Sponsors
Leads: Federico II University