Implementing Metabolomics Informed Diet on Inflammatory Bowel Disease Patients

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The effects of diet on inflammatory bowel disease is an under-studied area of research. The investigators are interested in further investigating the role that diet contributes to inflammatory bowel disease severity. The investigators will collect blood and stool samples from patients with inflammatory bowel disease (IBD) before and after diet changes. The stool samples will be analyzed using metabolomics and microbiome analysis to determine changes after the new diet has been implemented. The investigators will then compare changes in the patient's overall disease state by measuring markers of inflammation including C-reactive protein (CRP) and fecal calprotectin to determine how this diet affects the disease state.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years old or older

• Meet classification criteria for inflammatory bowel disease including those with mild to moderate Crohn's Disease as defined by a Crohn's disease activity index between 150-450, with fecal calprotectin\>250, within 1 month of enrollment.

Locations
United States
California
University of California, San Diego
RECRUITING
San Diego
Contact Information
Primary
Monica Guma, M.D., PhD
mguma@health.ucsd.edu
8588226523
Backup
Mehrnaz Aghili, M.D.
maghili@health.ucsd.edu
8582464721
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2028-08-01
Participants
Target number of participants: 90
Treatments
Experimental: Mediterranean Diet
Mediterranean Diet for 42 Days
Related Therapeutic Areas
Sponsors
Leads: University of California, San Diego

This content was sourced from clinicaltrials.gov