Application Research of Lactobacillus Reuteri in the Treatment of Inflammatory Bowel
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This project involves the use of oral Lactobacillus reuteri as an adjunct therapy for 8 weeks. Endoscopic observation of intestinal inflammation will be conducted at 1 month, 3 months, 6 months, and 12 months after the administration of the drug. Intestinal fluid will be collected endoscopically for 16S RNA analysis to assess changes in the gut microbiota. Inflammatory changes in the patients will be detected through peripheral blood tests, and fecal calprotectin levels will be measured to evaluate the progression of the disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Be over 18 years old
• Agree to sign informed consent; Have been diagnosed with IBD for at least 3 months but not more than 3 years -
Locations
Other Locations
China
Gastroenterology Department of Jiangsu Province （Suqian）Hospital
RECRUITING
Suqian
Contact Information
Primary
Huanhuan Chen, Doctor
775804281@qq.com
18351093039
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 50
Treatments
Experimental: Probiotic
Daily intervention with Limosilactobacillus reuteri LR08 (10 billion CFU, 2g) for 8 weeks, stored in a cool and dry place.
Placebo_comparator: Placebo
Every day to give 3 g maltodextrin intervention for 8 weeks. Store in a cool and dry place.
Related Therapeutic Areas
Sponsors
Leads: Wecare Probiotics Co., Ltd.